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Sharp can over-encapsulate solid oral dosage forms like tablets or capsules, back fill them with a suitable excipient and manufacture a placebo to match.

When you’re making the transition from placebo to active product, we offer a wide range of advanced, agile manufacturing capabilities. These include efficiently producing solid, liquid, cream and ointment products – and many more – in whatever quantities your business needs.

Our manufacturing teams are supported by high-calibre analytical labs at our Bethlehem research facility and partner sites across the EU, enabling constant monitoring of your product’s progress.

Whether you’re looking for a placebo to match your product or designing your trial dose to match an existing comparator, getting a good match can be almost impossible. That’s where we come in, we can support the scientific credibility of your clinical trial, maintaining the integrity of your double-blind study design.

Clinical manufacturing capabilities:

  • Wet or dry granulation and blending
  • Tablet compression and coating
  • Global comparator procurement
  • Manufacture of clinical supplies
  • Blending, encapsulation and over-encapsulation
  • Phase I-IV development and reformulations
  • Placebo manufacturing
  • Comparator blinding

Dosage forms we can manufacture:

  • Controlled-release tablets
  • Immediate-release tablets
  • Capsules
    • Multi-fill
    • Powders
    • Solids
    • Liquids
    • Semi-solids
    • Solid and liquid combination fills
  • Powders and dry powders
  • Suspensions
  • Emulsions
  • Creams
  • Ointments
  • Lotions

Talk to our expert team today about over encapsulation and placebo manufacturing

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